Aims and Objective: To see the incidence of generation of the induced membrane by Masquelet’s technique in long bone fracture with bone loss. To see the radiological union at fracture site in patients treated by Masquelet’s technique. To see the infection rate in patients treated with Masquelet’s technique. To see the complication in patient’s treated with Masquelet’s technique.

Material and Methods: 30 patients of segmental bone loss in long bone fractures with different aetiologies were treated using Masquelet technique. All patients undergone two stage procedures as described in Masquelet technique. Stage 1 surgery performed to generate the induced membrane. Through debridement, fixation of fracture and placement of antibiotic PMMA cement are the steps involved in stage 1. In stage 2 the removal of cement, placement of cortico-cancellous bone graft and careful closure of induced membrane was done. Primary fixation changed to definitive fixation using plates and intramedullary nails. Sequential radiographic union along with other complications of procedure was noted on follow-ups.

Results: Overall incidence of generation of induced membrane was 100%. Mean age at presentation was 41.23 years with (SD) standard deviation of 11.464. The male population if the study was 27/30 i.e. 90% while the female proportion was 3/30 i.e.10%. Most common aetiology of segmental bone loss in long bone fracture was roadside accidents i.e. 66.7% which was followed by septic non-union of fractures i.e. 33.3%. Mean time to achieve radiological union at fracture site in our study was 5.87 months with standard deviation of 1.795. Complications in the study were pin track infection, superficial and deep infections, flap necrosis and implant failure.

Conclusion: Overall union was achievable in cases of bone loss in long bone fractures. Masquelet technique gives promising results in bone loss cases upto 8 cm. Patient compliance was better throughout the study as the procedure is simple to understand, easy to apply no special expertise needed. We recommend this technique for bone loss upto 8 cm. However, for larger bone defects we recommend Ilizarov/LRS.