Background: Tourniquet application is still a common practice in total knee arthroplasty surgery despite being associated with several adverse effects. We evaluated the effects of tourniquet use on hematological parameter and knee range of motion in total knee arthroplasty.

Materials & Methods: This prospective, randomized study comprised 60 patients who underwent a primary total knee replacement arthroplasty in Era’s Lucknow Medical College between December 2016 to August 2018. Thirty patients were operated with the use of an arterial tourniquet (group A), and 30 patients without the use of a tourniquet (group B). Hemoglobin and haematocrit was recorded pre-operatively and at the first and third day post-operatively. Overall blood loss was calculated as the sum of compensated and non-compensated blood loss.

Results: Upon comparison of the Mean measured blood loss in suction drainage between the two groups statistical significance was noted (p =0.020) Patient in the tourniquet group had less blood loss, in suction drain but on comparison of overall blood loss no significant difference were found in these groups.

Conclusion: we conclude in our study that Total knee replacement can be safely done without tourniquet with respect to hematological parameter and has better knee range of motion in early postoperative period.